The Western Highway around the Lake passes through the village.
There are three ferry services: from Como to Colico; the central lake services; the car ferry service between Bellagio and Cadenabbia which is about 10 minutes' walk from Tremezzo
There is also a lot of daily bus connection operated by ASF Autolinee to Como - route C10 (http://www.asfautolinee.it/Lineeeorari/Orariolineeinpdf/Reteextraurbana/tabid/245/language/en-US/Default.aspx)
To join Tremezzo from Bergamo-Orio al Serio Airport, take the LAKE COMO express bus service (http://www.lakecomoexpress.it/en/Home/tabid/662/language/it-IT/Default.aspx)